5 things to know about 'Dallas' star Larry Hagman

Five things to know about "Dallas" star Larry Hagman:

1. HIS FAMOUS MOM

Hagman was the son of singer-actress Mary Martin, who starred in such classics as "South Pacific" and "Peter Pan." Martin was still in her teens when he was born in 1931 during her marriage to attorney Ben Hagman.

2. HOW HE FIRST GAINED FAME

Years before "Dallas," Hagman was on "I Dream of Jeannie," in which he played an astronaut whose life is disrupted when he finds a comely genie, portrayed by Barbara Eden, and takes her home to live with him.

3. HIS REAL LIFE ADVOCACY

Hagman was diagnosed with cirrhosis of the liver and acknowledged that he drank heavily for years. He had a transplant after a malignant tumor was discovered in 1995, and it turned him into an advocate for organ donation and a hospital volunteer. He was also an anti-smoking activist who took part in "Great American Smoke-Out" campaigns.

4. WHAT HE WANTED ON J.R.'s TOMBSTONE

"It should say: 'Here lies upright citizen J.R. Ewing. This is the only deal he ever lost,'" Hagman said in 1988.

5. WHO SHOT J.R.?

The answer to that cliffhanger was one of the most-watched television events in history. It was J.R.'s sister-in-law, Kristin (Mary Crosby) ? he had made her pregnant, then threatened to frame her as a prostitute unless she left town.

Source: http://news.yahoo.com/5-things-know-dallas-star-larry-hagman-155801956.html

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Holiday shopping season off to record start

FILE -In this Friday, Nov. 23, 2012, file photo, Black Friday shoppers pour into the Valley River Center mall for the Midnight Madness sale, in Eugene, Ore. U.S. shoppers hit stores and websites at record numbers over the four-day Thanksgiving weekend, according to a survey released by the National Retail Federation on Sunday. They were attracted by retailers' efforts to make shopping easier, including opening stores on Thanksgiving evening, updating mobile shopping applications for smartphones and tablets, and expanding shipping and layaway options. (AP Photo/The Register-Guard, Brian Davies)

FILE -In this Friday, Nov. 23, 2012, file photo, Black Friday shoppers pour into the Valley River Center mall for the Midnight Madness sale, in Eugene, Ore. U.S. shoppers hit stores and websites at record numbers over the four-day Thanksgiving weekend, according to a survey released by the National Retail Federation on Sunday. They were attracted by retailers' efforts to make shopping easier, including opening stores on Thanksgiving evening, updating mobile shopping applications for smartphones and tablets, and expanding shipping and layaway options. (AP Photo/The Register-Guard, Brian Davies)

FILE - In this Thursday, Nov. 22, 2012, file photo, shoppers wait on a check-out line in the Times Square Toys-R-Us store after doors were opened to the public at 8 p.m., in New York. U.S. shoppers hit stores and websites at record numbers over the four-day Thanksgiving weekend, according to a survey released by the National Retail Federation on Sunday. They were attracted by retailers' efforts to make shopping easier, including opening stores on Thanksgiving evening, updating mobile shopping applications for smartphones and tablets, and expanding shipping and layaway options. (AP Photo/John Minchillo)

NEW YORK (AP) ? If you make holiday shopping convenient, Americans will come in droves.

It's estimated that U.S. shoppers hit stores and websites at record numbers over the Thanksgiving weekend, according to a survey released by the National Retail Federation on Sunday. They were attracted by retailers' efforts to make shopping easier, including opening stores on Thanksgiving evening, updating mobile shopping applications for smartphones and tablets, and expanding shipping and layaway options.

All told, a record 247 million shoppers visited stores and websites over the four-day weekend starting on Thanksgiving, up 9.2 percent of last year, according to a survey of 4,000 shoppers that was conducted by research firm BIGinsight for the trade group. Americans spent more too: The average holiday shopper spent $423 over the entire weekend, up from $398 last year. Total spending over the four-day weekend totaled $59.1 billion, up 12.8 percent from 2011.

Caitlyn Maguire, 21, was one of the shoppers that took advantage of all the new conveniences of shopping this year. Maguire, who lives in New York, began buying on Thanksgiving night at Target's East Harlem store. During the two-hour wait in line, she also bought items on her iPhone on Amazon.com. On Friday, she picked up a few toys at Toys R Us. And on Saturday she was out at the stores again.

"I'm basically done," said Maguire, who spent about $400 over the weekend.

The results for the weekend appear to show that retailers' efforts to make shopping effortless for U.S. consumers during the holiday shopping season worked. Retailers upped the ante in order to give Americans more reasons to shop. Stores feared that consumers might not spend because of the weak job market and worries that tax increases and budget cuts will take effect if Congress fails to reach a budget deal by January.

Retailers, which can make up to 40 percent of their annual revenue in November and December, were hoping Thanksgiving openings and other incentives would help boost what's expected to be a difficult holiday shopping season. The National Retail Federation estimates that overall sales in November and December will rise 4.1 percent this year to $586.1 billion. That's more than a percentage point lower than the growth in each of the past two years, and the smallest increase since 2009, when sales were nearly flat.

Matthew Shay, president and CEO of the National Retail Federation, said retailers can be encouraged by the first weekend of the holiday shopping season.

"Retailers and consumers both won this weekend, especially on Thanksgiving," he said.

Here were the trends that emerged over the weekend:

? Online wave: According to comScore, which tracks online spending, online sales rose 26 percent to $1.04 billion on Black Friday compared with a year ago. On Thanksgiving, online sales rose 32 percent from last year to $633 million. And online sales on Black Friday were up 26 percent from the same day last year to $1.042 billion. It was the first time online sales on Black Friday surpassed $1 billion.

? Thanksgiving shopping: Many stores, including Toys R Us and Target, opened on Thanksgiving evening this year. No data is out yet about how much shoppers spent on that day, but it appears that consumers took advantage of the earlier start: According to the National Retail Federation's survey, the number of people who shopped on Thanksgiving rose 23.1 percent. That compares with a 3.1 percent increase for Black Friday.

Linda and James Michaels of Portland, Ore., were among those shopping on Thanksgiving. They hit up the big sales on the day and got everything they were hoping for that night.

They picked up remote control cars and some Mickey Mouse items on sale at Toys R Us. Then they went a few doors down to Target and scored the last Operation game on sale for $7. They were even able to pick up some pajamas and shoes along the way for the kids. In total they spent about $300.

"I felt lucky that I caught the deals and there was no craziness, no fighting," said Linda Michaels. "I was nervous."

ShopperTrak, which analyzes customer traffic at 40,000 U.S. stores, plans to release sales data for Thanksgiving later this week, but the firm is estimating that retailers generated $700 million in sales on the holiday.

? Black Friday flop: It appears that the Thanksgiving openings may have hurt sales on the day after.

Black Friday is still expected to be the biggest shopping day of the year, but sales on that day slipped to $11.2 billion, down 1.8 percent from last year, according to ShopperTrak. That's below ShopperTrak's estimate that Black Friday sales would rise 3.8 percent to $11.4 billion.

Karen MacDonald, a spokeswoman at Taubman Centers, which operates 28 malls across the country, said that Thanksgiving openings hurt business. Based on a sampling of 10 malls, sales growth was unchanged up to mid-single digits on Friday, and unchanged up to low single digit on Saturday.

"It was a different feeling," she said. "It was a good Black Friday, but I don't think it was great."

The disappointing sales on Black Friday may have been the result of shoppers like Miguel Garcia, a 40-year-old office coordinator.

"I can't deal with all that craziness," said Garcia, who was at a Target in the Bronx borough of New York City on Saturday. "Compared to what I saw on TV yesterday, this is so much more comfortable and relaxed. I can actually think straight and compare prices."

___

AP writers Rodrigue Ngowi in Watertown, Mass., Juan Carolos Llorca in El Paso, Texas, and Candice Choi in New York contributed to this report

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-11-25-US--Holiday%20Shopping/id-3049224b6ab249fe89c2f0b09bc92678

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New 3-D movie technology: are viewers ready?

14 hrs.

Emily Sohn , Discovery News

When the?3-D version of "The Hobbit: An Unexpected Journey" debuts in movie theaters on Dec.?14, the film will likely wow viewers with its special effects. But audiences at select theaters will get even more bang for their buck: they?ll be the first to witness a new technology that displays images at a rate of 48 frames per second, twice as fast as the current standard.

The new display rate is sure to look different. Whether audiences will like it is less certain. So far, early reviews have been mixed, according to 3D Focus, a website that tracks changes in 3-D-viewing technology.?

BLOG: Is 3-D vision bad for you??

Some people think the effects look "too real." For others, eyestrain, headaches, nausea and other discomforts are as much of a hazard as they were with the older technologies. That's because most films that are designed to make images look like they are popping out of the screen work by showing each eye different pictures at different times. That forces the brain to merge conflicting messages -- an obstacle that 3-D studios are still working to overcome.

"People really differ," said Marty Banks, a vision scientist at the University of California, Berkeley. "Some people just don't get it and they're fine. Other people are fairly uncomfortable. The industry is really worried about this. They're listening to us?scientists and they?re taking our advice."

ll movies, whether "2-D" or "3-D" create the illusion of movement by flashing one still image after another onto the screen at a rate that is fast enough to fool our brains into seeing action. If the sequence of images is presented too slowly, the result is a shaky effect called "judder" that can sometimes look like a double image.

3-D technology (which Banks prefers to call stereo-3-D or S3-D because even "2-D" movies look three-dimensional) raises the risk for judder because these films usually show screen shots in an alternating sequence to one eye at a time. First the left eye sees an image, then the right eye sees one, then the left eye sees the next image, and so on.

With the latest generation of 3-D glasses, polarizing filters allow each eye to see light coming from just one direction, and screen shots are displayed so that a single lens is targeted at a time. When one eye is stimulated, the other eye is presented with darkness.

It's up to the brain to put everything together into a coherent picture. But with each eye seeing alternating flashes of brightness and darkness, jumpy judder can creep in, causing distraction or discomfort.

BLOG: Sony?s 3-D digital recording binoculars

To solve that problem, 3-D films that are shot at a standard 24 frames per second actually show the left eye a single image three times in a row with flashes of darkness in between. Then the right eye gets its image three times in a row, and that pattern continues for the entire film. This "triple flashing" allows the screen to display 72 frames per second, which reduces flicker effects.

For the new Hobbit, director Peter Jackson used new technology to film at 48 frames per second instead of 24. In real life, our visual systems take in information continuously, and some experts speculate that images will need to be captured at more than 100 or even 150 frames per second before a movie looks truly real. But with any increase in frame-rate speed, motion should look smoother and more realistic.

"As you increase the rate of new incoming data, you're getting closer and closer to the real world," Banks said. "At some rate, you will get to the point where you can?t tell the difference."

But first, moviemakers have some technical issues to deal with.

One question, Engle said, is whether the technological limitations of the projectors used by most theaters will require them to use fewer flashes for each eye before switching to the other eye?s image????a switch that could actually cause new stuttering problems.

NEWS: Underwater movie maker: Shaun MacGillivray

Some theaters use a dual-projector set-up that gets around that issue by showing images to both eyes at the same time, and in those cases, Engle said, the results should be spectacular. But theaters that use a single projector to display 3-D movies will have some new decisions to make, and audiences might not be universally happy about the final product.

"You have to be careful what you wish for," said Rob Engle, 3-D supervisor at a major film studio in Burbank, Calif. "If you have to make compromises in order to increase the frame rate by decreasing the flash rate, you start to run into trade-offs."

As higher frame rates lead to more realism, dismay is also cropping up among people who are used to seeing films that look like films rather than television or real life. Similar complaints have emerged whenever filmmaking technology has risen to a new level over the decades.

"Every time we've moved closer to reality by adding sound, adding color or getting rid of scratches, in the end, the audience has accepted it and there's no going back," Banks said. "I think the same is going to be true here.

"In the end, we all want immersion. We want to feel like we're in that scene and closer to reality. I think once people see it, they are going to go, 'Wow. I want that.'"

Source: http://www.nbcnews.com/technology/technolog/new-3-d-movie-technology-are-viewers-ready-1C7206887

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Pope elevates 6 cardinals to choose successor

Pope Benedict XVI, center, blesses faithful during his weekly general audience at the Vatican, Wednesday, Nov. 21, 2012. The Pontiff says he is praying for victims of the conflict between Israel and Gaza militants and gave his encouragement for efforts to obtain a cease-fire and negotiations. (AP Photo/Gregorio Borgia)

Pope Benedict XVI, center, blesses faithful during his weekly general audience at the Vatican, Wednesday, Nov. 21, 2012. The Pontiff says he is praying for victims of the conflict between Israel and Gaza militants and gave his encouragement for efforts to obtain a cease-fire and negotiations. (AP Photo/Gregorio Borgia)

VATICAN CITY (AP) ? Six new cardinals are joining the elite club of churchmen who will elect the next pope, bringing a more geographically diverse mix into the European-dominated College of Cardinals.

Pope Benedict XVI will formally elevate the six at a ceremony Saturday, bestowing red hats and gold rings on prelates from Colombia, India, Lebanon, Nigeria, the Philippines and U.S.

In explaining his choices for this "little consistory," Benedict said he was essentially completing his last cardinal-making ceremony held in February, when he elevated 22 cardinals, the vast majority of them European archbishops and Vatican bureaucrats.

The six new cardinals "show that the church is the church of all peoples and speaks in all languages," Benedict said last month. "It's not the church of one continent, but a universal church."

That said, the College of Cardinals remains heavily European even with the new additions: Of the 120 cardinals under age 80 and thus eligible to vote in a conclave to elect a new pope, more than half ? 62 ? are European. Critics have complained that the College of Cardinals no longer represents the church, since Catholicism is growing in Asia and Africa but is in crisis in much of Europe.

With the new additions, the College of Cardinals is a tad more multinational: Latin America, which boasts half of the world's Catholics, now has 21 voting-age cardinals; North America, 14; Africa, 11; Asia, 11; and Oceana, one.

Among the six new cardinals is Archbishop James Harvey, the American prefect of the papal household. As prefect, Harvey was the direct superior of the pope's former butler, Paolo Gabriele, who is serving an 18 month prison sentence in a Vatican jail for stealing the pope's private papers and leaking them to a reporter in the greatest Vatican security breach in modern times.

The Vatican spokesman has denied Harvey, 63, is leaving because of the scandal. But on the day the pope announced Harvey would be made cardinal, he also said he would leave the Vatican to take up duties as the archpriest of one of the Vatican's four Roman basilicas. Such a face-saving promotion-removal is not an uncommon Vatican personnel move.

Harvey's departure has led to much speculation about who would replace him in the delicate job of organizing the pope's daily schedule and arranging audiences.

Aside from Harvey, the new cardinals are: Abuja, Nigeria Archbishop John Olorunfemi Onaiyekan; Bogota, Colombia Archbishop Ruben Salazar Gomez; Manila, Philippines Archbishop Luis Antonio Tagle; Patriarch of Antioch of the Maronites in Lebanon, His Beatitude Bechara Boutros Rai; and the major Archbishop of the Trivandrum of the Siro-Malankaresi in India, His Beatitude Baselios Cleemis Thottunkal.

Cardinals serve as the pope's closest advisers, but their main task is to elect a new pope.

The six new cardinals are all under age 80. Their nominations bring the number of voting-age cardinals to 120, 67 of whom were named by Benedict, all but ensuring that his successor will be chosen from a group of like-minded prelates.

Saturday's consistory marks the first time in decades that not a single European or Italian has been made a cardinal ? a statistic that has not gone unnoticed in Italy. Italy still has the lions' share of cardinals, though, with 28 voting-age "princes" of the church.

___

Follow Nicole Winfield at www.twitter.com/nwinfield

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-11-24-Vatican-New%20Cardinals/id-e360c2bb0220423cad7ef9b622314322

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Online Shoppers Not Replacing In-Store Buyers | News - Indiana ...

Photo: Shein (Flickr)

Black Friday shoppers get a start on holiday shopping at a Best Buy.

Though online shopping has increased, it has not taken the place of in-store holiday shopping.

Over the past several years internet holiday sales have increased. Economist Kyle Anderson says there has been a shift toward online shopping, but it?s not reducing the number of Black Friday?s in-store shoppers. One of the reasons people still buy products in-store, he says, is customers realize they could end up paying more online because of shipping costs.

?A lot of times online retailers will say it?s offset by shipping,? he says. ?So it?s kind of, well I don?t pay the 7 percent sales tax, but I do pay shipping costs which might be that much or more and so it all kind of washes out.?

Hoosiers do not pay online sales tax, providing an incentive to buy online. But Best Buy General Manager Joe Marcoux says he still expects his store to see eight to 10 times more business than a normal Friday.

?There?s a new Wii gaming system that launched this week on Sunday, flat panel TV?s are still great because the prices are so good,? he says. ?Everything?s going to be hot. The tablet and computing category for us is the big category right now. Mobile phones are exploding with the launch of Windows 8 as well, so if it?s a tablet, if it?s a computer, if it?s a gaming system or a flat panel TV it?s going to sell well.?

And when it comes to pricing, Anderson says customers should remember that local retailers also pay for shipping, but i is already built into the shelf price.

Source: http://indianapublicmedia.org/news/online-shopping-replacing-instore-buyers-40643/

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Black Friday politics: Do some stores lean Democratic or Republican?

Black Friday is upon us, which means a break from politics, right? Nope. DC Decoder offers you a by-the-numbers look at how some top holiday retailers spend their money politically.

By Peter Grier,?Staff writer / November 23, 2012

Shoppers wait in a checkout line in the Times Square Toys R Us store after doors were opened to the public at 8 p.m. on Thursday in New York.

John Minchillo/AP

Enlarge

Black Friday: It?s a day in which most American citizens put aside politics in pursuit of shopping bargains. But in Washington we can sort almost anything in the US in terms of partisan proclivity, and temples of commerce are no exception. Want to know whether the big box store where you?re waiting in line leans Democratic or Republican? ?The folks at the invaluable Center for Responsive Politics have compiled a handy guide based on campaign contributions.

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Toys R Us, for instance, seems a solidly blue store. Self-identified employees of the store gave $39,000 to political candidates in the 2012 election cycle, and $36,000 of that went to Democrats.

Dig into the numbers though, and you?ll see that Toys R Us is not so much Democratic as Klobucharian. All that $36,000 went to one candidate, Sen. Amy Klobuchar (D) of Minnesota. (That?s kind of odd, isn?t it? The retailer?s corporate headquarters are in New Jersey.) Other than that, Mitt Romney got $1,750 from Toys R Us workers. President Obama got zilch, according to CRP?s Open Secrets blog.

Macy?s employees, on the other hand, were big Obama fans. They donated $28,870 to the president?s reelection campaign, as opposed to $16,390 to GOP nominee Mr. Romney. This Democratic lean was counterbalanced to a certain extent by the store?s corporate political action committee, however. (Toys R Us doesn?t appear to have a central PAC.) Macy?s PAC gave $12,000 to Republicans, and $4,000 to Democrats.

Best Buy seems more of a red retailer. Both it s employees and the company?s PAC had a slight preference for Republicans, according to CRP. Store employees gave $17,662 to Democrats and $22,419 to the GOP, for instance.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/nYy539pCRQE/Black-Friday-politics-Do-some-stores-lean-Democratic-or-Republican

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yahsat gears up to launch ka-band satellite broadband ... - iBotswana

Thursday, 22 November 2012 Staff Author | Published in: World News JUBA, South Sudan, November 22, 2012/African Press Organization (APO)/ -- Yahsat (http://www.yahsat.ae), the Abu Dhabi, UAE, based satellite operator, is gearing up to launch its innovative YahClick ?broadband everyone? satellite service in South Sudan over the coming months. The hotly anticipated service is set to provide wide reaching, high performance, satellite broadband Internet to unserved and underserved locations and communities across the country.

Logo: http://www.photos.apo-opa.com/plog-content/images/apo/logos/yahsat.jpg

Yahsat selected local based Internet Service Provider RCS-Communication as their Service Partner for South Sudan based on RCS-Communication's in-country experience, proven track record of delivering new and innovative services and a common focus to bring faster and more affordable Internet connectivity to a wide range of users.

Commenting on the upcoming launch, Tareq Abdul Raheem Al Hosani, Yahsat CEO, stated,

?As the world's youngest country, South Sudan is facing multiple infrastructure building priorities. YahClick brings internet connectivity instantly to the population, irrespective of the state of the local telecommunications infrastructure that is within their reach. YahClick therefore fast tracks connectivity to this young country beyond what is humanly possible with the time and expense it takes to expand fixed or wireless internet solutions.

?Providing much needed internet connectivity to a new nation presents YahClick with tremendous opportunity as well as pride in helping address at least one of the many requirements of this young country. Having affordable, reliable and instantly available high performance internet will be a fundamental tool to help new and established businesses and individuals in South Sudan achieve their full potential.?

Flippie Odendal, RCS-Communication, Republic of South Sudan, Managing Director stated, ?YahClick is the first Ka-band satellite internet service in Africa that offers true broadband speeds at affordable prices. We are proud to bring the service to South Sudan and anticipate a wide interest across the country.?

?Based on anticipated growth we will be adding and training VSAT technicians and support staff (with a focus on South Sudanese candidates) to our existing team. Parallel to this process we will be running extensive tests of the new service and processes over the next months to ensure all aspects are working well before the service is made available to clients.?

Yahsat believes in providing individuals with a platform to access information no matter their geographical location, thus enabling them, through the power of information to enhance and help change their world in order for them to have a positive economic and societal impact on the world around them.

Al Hosani added, ?Our YahClick service aims to bring broadband to everyone and deliver the power of Internet collaboration to individuals and global communities across three continents. We believe it is the right of every individual to have high speed and reliable Internet. Our team is excited about the prospect of helping connect a portion of the world's un-served communities in the Republic of South Sudan and providing them with the tools to aid their own success.?

Distributed by the African Press Organization on behalf of Al Yah Satellite Communications Company PrJSC ?Yahsat?.

For more information on the YahClick service log onto http://www.yahsat.ae/YahClick or write to [email?protected]

About Al Yah Satellite Communications Company PrJSC ?Yahsat?

Yahsat (http://www.yahsat.ae) provides multipurpose satellite solutions (commercial and government) for broadband, broadcast, military, and communications use across the Middle East, Africa and South West Asia. Based in Abu Dhabi, UAE and wholly owned by Mubadala Development Company PJSC (http://www.mubadala.ae), the investment vehicle of the Government of Abu Dhabi, Yahsat is the first company in the Middle East and Africa to offer multi-purpose satellite services:

? YahClick - the satellite broadband service

? YahSecure - the government satellite service

? YahLink - the satellite connectivity service

? YahService - end to end managed satellite solutions

? YahCarrier ? satellite solutions for telecommunications carriers

Yahsat's first satellite Y1A was successfully launched in April 2011 and its second satellite Y1B was successfully launched in April 2012. YahClick began roll out in July 2012, serving 28 countries across the Middle East, Africa, Central and South West Asia with reliable and cost effective satellite broadband connectivity in urban, rural and remote areas.

About RCS-Radio & Satellite Communication Ltd ?RCS-Communication?

The RCS business group consists of different legal entities operating in a number of African countries. The first business entity was established in Uganda in 1996.

RCS-Communication (http://www.rcs-communication.com) is a professional ICT (Information Communication Technologies) company that offers a wide range of Internet connectivity, mobile satellite and other ICT solutions in partnership with selected suppliers and service partners across East and Central Africa.

RCS-Communication's focus is on businesses and organisations looking for a service provider that understands the terrain, accepts responsibility for performance and ensures future relevance for clients in a fast-changing world.

Press contacts

Yahsat:

Sarah Mheidly

Hill + Knowlton Strategies, Abu Dhabi

Phone: 971 55 217 7011

Email: [email?protected]

World

Minister for Africa comments after meeting with Rwanda's?...

LONDON, United-Kingdom, November 23, 2012/African Press Organization (APO)/ -- Minister for Africa, Mark Simmonds, arrived in Kigali today for meetings following the joint communiqu? agreed by Presidents Museveni, Kagame and Kabila yesterday in Uganda. Following his meeting with His Excellency President Paul Kagame, Mr Simmonds said: "I welcome the leadership?

Source: http://www.ibotswana.co.bw/news/world/item/23959-yahsat-gears-up-to-launch-ka-band-satellite-broadband-in-south-sudan.html

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Study reveals the proteins expressed by human cytomegalovirus

Friday, November 23, 2012

New findings reveal the surprisingly complex protein-coding capacity of the human cytomegalovirus, or HCMV, and provide the first steps toward understanding how the virus manipulates human cells during infection. The genome of the HCMV was first sequenced over 20 years ago, but researchers have now investigated the proteome?the complete set of expressed proteins?of this common pathogen as well.

HCMV is an incredibly successful virus, and it infects most humans on the planet. Birth defects and disease, however, are only known to occur in newborn infants and adults with compromised immune systems, respectively. But, the pathogen also has one of the largest viral genomes on record, with a massive 240,000 base pairs of DNA. (For comparison, the genome of the poliovirus only contains about 7,500 base pairs.)

Noam Stern-Ginossar from the University of California in San Francisco, along with colleagues from the United States and Germany, used a combination of techniques, including ribosome profiling and mass spectrometry, to study HCMV's proteome. The method could be used to investigate proteins produced by other viruses as well, they say.

The researchers' findings appear in the 23 November issue of the journal Science, which is published by AAAS, the nonprofit science society.

"The genome of a virus is just a starting point," explained Jonathan Weissman from the University of California, a co-author of the Science report. "Understanding what proteins are encoded by that genome allows us to start thinking about what the virus does and how we can interfere with it? Each of the proteins we've identified has the potential to tell us how this virus is manipulating its host cell."

Stern-Ginossar and the other researchers suspected that existing maps of HCMV's protein-coding potential, based largely on computational methods, were far from complete. So, they began mapping the positions of ribosomes?the cellular organelles in which proteins are synthesized?during an HCMV infection of human fibroblast cells. With the resulting map, Stern-Ginossar and her colleagues discovered templates for hundreds of previously unidentified proteins that were encoded in corresponding DNA segments of the viral genome, known as open reading frames.

Surprisingly, the researchers found that many of these open reading frames encode for exceptionally short protein sequences (fewer than 100 amino acids). And some of the newly identified open reading frames were even hiding inside other open reading frames, they say.

"A key finding of our work is that each of these templates can encode more than one protein," said Annette Michalski from the Max Planck Institute of Biochemistry in Martinsried, Germany, another co-author of the Science report. "And these extremely short proteins might be more common than we expect."

The researchers applied mass spectrometry to confirm the presence of many unknown viral proteins that had been predicted by mapping the ribosome positions.

In the future, this coupling of ribosome profiling with mass spectrometry might be used to investigate the proteomes of other complex viruses. Eventually, such information could be used to understand how different viruses hijack their hosts' cells for their own purposes.

###

American Association for the Advancement of Science: http://www.aaas.org

Thanks to American Association for the Advancement of Science for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/125441/Study_reveals_the_proteins_expressed_by_human_cytomegalovirus

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Rising Won has South Korea Worried | Benzinga

South Korea's currency, the won, has been rising against the currencies of its major trading partners, China, the United States, the European Union and Japan. South Korea's economy is heavily dependent upon exports, which made up 44.6 percent of GDP in 2010.

Since the beginning of the year, the South Korean won has risen by 6.4 percent against the U.S. dollar, 5.5 percent against the euro, six percent against the Chinese yuan and 13 percent against the Japanese yen.

South Korean government officials are worried. So much so that they intervened in the currency market on Thursday, buying up to $1 billion in an effort to weaken the won, according to the Financial Times.

The FT reported that South Korean officials are considering tightening restrictions on trading currency derivatives to curb the won's volatility in the currency market. South Korean deputy finance minister Choi Jong-gu, told the FT, ?Recent movement of the market shows that the volatility continues to increase, mainly driven by some expectation that the won will continue to appreciate further.?

The rapid appreciation of the won against the U.S. dollar affects Korea's trade with two of its major trading partners, the United States, which accounts for 11.1 percent of South Korea's exports, and China, which is South Korea's biggest export market, taking 25.8 percent of South Korea's total exports.

China's currency, the yuan, is not freely convertible and trades in a designated band around the U.S. dollar set by Chinese monetary authorities. Unless China widens the trading band, which they do on occasion, the yuan will generally rise or fall against other currencies in line with the U.S. dollar.

That means that, all else being equal, South Korean companies are earning about six percent less on nearly 37 percent of their exports than they were at the beginning of the year. To put it another way, if prices remain stable, South Korea has to increase export volume by six percent just to stay where they were in January.

That is why the sharp appreciation of the South Korean won against the Japanese yen is so important.

Japan is South Korea's second largest trading partner after China, accounting for 10.7 percent of South Korea's total trade. But, of South Korea's four main trading partners, Japan is the only one that runs a trade surplus with South Korea.

South Korea imports large quantities of industrial goods, particularly chemicals and machinery, from Japan. Much of this is incorporated into South Korean products that are exported to the rest of the world, including Japan.

Much of South Korea's competitive advantage in automobiles, construction equipment, electronics and steel comes from the fact that the won has been persistently weak against the Japanese yen for the past five years. If the exact same LCD TV were built in South Korea and Japan, the Korean model would be much cheaper because of the weak won.

With the yen now 13 percent cheaper against the won than it was at the beginning of the year, South Korea is losing some of its competitive edge in its export markets. If currency Is less of a factor, other competitive advantages and disadvantages between Korean and Japanese companies come into play.

If traders want to take a view on the trend in the South Korean won, one way to do this is through a pair trade between the iShares MSCI South Korea Index (NYSE: EWY) and the iShares MSCI Japan Index (NYSE: EWJ).

If you think the appreciation of the won against the yen will continue, they you would short EWY and go long EWJ. If you think the trend will reverse, then short EWJ and go long EWY.

Regardless of your view, the seldom-watched Japanese yen/South Korean won exchange rate will be the key to which country will have a relative competitive advantage in 2013. Keep your eye on the chart below:

Chart from Yahoo Finance

(c) 2012 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

Posted in: Long Ideas, News, Short Ideas, Emerging Market ETFs, Global, Econ #s, Trading Ideas, ETFs, Best of Benzinga

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Source: http://www.benzinga.com/trading-ideas/long-ideas/12/11/3115201/rising-won-has-south-korea-worried

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The X Factor Recap: Giving Thanks For...

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Alistair Overeem, Golden Glory settle legal issues - MMA Fighting

UFC heavyweight Alistair Overeem continues attempts to chart a smoother path towards his future. A few days after UFC president Dana White revealed that the former Strikeforce champion would likely return from his suspension to face Antonio Silva in February, Overeem and his former fight camp and management team at Golden Glory have resolved their outstanding legal issues, reaching a settlement to dismiss dueling lawsuits.

In a press release distributed to the media by Golden Glory through their attorney Roderick J. Lindblom, it was announced the two sides reached an "amicable resolution" to their dispute.

Overeem originally sued Golden Glory last November, alleging that they had refused to pay over $151,000 of money he was owed. He was also seeking a court order to break his existing management contract with them. Golden Glory eventually counter-sued, saying his claims were "scurrilous."

Overeem had been part of the team's stable for over a decade, winning not only the Strikeforce belt but also championships in DREAM and K-1, where he was the World Grand Prix titlist.

According to Golden Glory's release, there were no fewer than six law firms involved in the messy suit.

"Everyone worked extremely hard to resolve these matters so that Management/Promoter KOI/Golden Glory and Bas Boon can walk away and move forward with the Glory World Series Promotion in Europe, Japan and the USA and Alistair Overeem can concentrate on his fighting career with his new manager Glen Robinson at Authentic Sports Management and his new team the Blackzilians," Lindblom said in a statement.

While those legal woes are behind him, the 32-year-old Overeem will still need to stand in front of the Nevada state athletic commission for re-licensure before his UFC 156 bout on Super Bowl Saturday can be made official. He is still currently serving a suspension after testing positive for elevated levels of testosterone in a surprise March screening. He may reapply for a license following the expiration of his suspension on Dec. 27.

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Source: http://www.mmafighting.com/2012/11/21/3675500/alistair-overeem-golden-glory-settle-legal-issues

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95% Diana Vreeland: The Eye Has To Travel

All Critics (61) | Top Critics (24) | Fresh (58) | Rotten (3)

Her life, and her work, transcended what we think of as "fashion." Diana Vreeland: The Eye Has to Travel celebrates a unique and uniquely determined woman.

Many people remember some of Diana Vreeland's famous pronouncements ("I adore pink! It is the navy blue of India!") but few remember actually hearing her speak. The documentary Diana Vreeland: The Eye Has to Travel takes care of that.

For fashionphiles and pop culture vultures, there's much to devour.

Diana Vreeland is both history lesson and sentimental love letter to a fashion titan.

Legendary fashion editor Diana Vreeland was the consummate dreamer, a romantic who never looked back and propelled society forward.

A feast for fashion-history buffs and anyone who applauds unstoppable eccentricity.

She wanted you to look and look again, and this film is full of images which make you do just that.

There's something marvellously comic about her, an effect reinforced by her refined yet raucous baritone voice.

This pleasurable documentary is jammed packed with images from magazines, photoshoots and newsreels of a life well lived, but also lots of historical footage of the life Vreeland imagined she had too.

...more of an energetic and affectionate sketch than a revealing portrait of this oversized personality, but one has to wonder if the woman who celebrated glittering surfaces would have wanted it any other way.

This fascinating documentary reveals that Vreeland (who died in 1989, aged 86) was an original: a dynamic woman with energy to spare and an infectious lust for life

What makes this such a joy to watch is not just the timeline of fashion highlights, but Vreeland's unique perspective on life.

The filmmakers have done a fine job corralling so many fantastic tales from Vreeland's life.

"Diana Vreeland: The Eye Has to Travel" is an intriguing portrait of a true original; you only wish the movie had half the color and verve of its subject.

A lively movie, and in the case of its appearance-obsessed subject, it feels right that all it does is skim the surface.

[Vreeland's] influence on twentieth-century culture was large, and it's celebrated here with affection, dedication and skill--but very little critical detachment.

Though unwilling to dig too deeply into what seems an imperfect private life, it still serves as a splendid introduction to a unique personality.

A poignant portrait of an inveterate iconoclast who couldn't help but push the envelope.

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Source: http://www.rottentomatoes.com/m/diana_vreeland_the_eye_has_to_travel_2012/

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That didn?t take long ? Obama reverses himself on Israel (Powerlineblog)

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Christmas Family House Party at Macdonald Berystede Hotel, near ...

Take the family to an all inclusive two or three night Christmas house party at the luxurious 4* Macdonald Berystede Hotel & Spa, near Royal Windsor where fun activities, lively entertainment and meals are included for all ages.

Set in wooded grounds within the beautiful Thames valley, the Macdonald Berystede has the timeless elegance of a stately home with its oak panelled lounge and roaring open fire. Combine this with excellent family amenities, the indulgence of a luxury spa and award-winning food and it?s the perfect retreat to relax and be pampered during the festive season.

The house party programme includes many extras for children such as a door stocking with a gift in the bedroom; a Christmas fairytale reading by the fire on Christmas Eve; Santa Claus grotto in the grounds and a visit by Santa himself bearing a present on Christmas Day, plus a trip to see Jack and the Beanstalk pantomime in Windsor?s Theatre Royal on Boxing Day followed by tea and a family quiz. In addition, there are special family swim times in the indoor pool and children can enjoy their own dishes in the restaurant plus unlimited tea, coffee and soft drinks; a selection of board games, cards and puzzles will also be available to play throughout their stay.

Most meals also included starting with a traditional cream tea in the comfy lounge on arrival Christmas Eve. Celebrations get underway at 7pm when the champagne flows at a sparkling reception with entertainment by local carol singers, all followed by a superb three-course dinner in the AA Rosette Hyperion Restaurant.

After breakfast on Christmas morning, there?s plenty of time to open presents, or take a walk in the hotel?s landscaped grounds, to build up an appetite for the four-course festive lunch.? And in case anyone is still hungry, tea and Christmas cake will be served in the Diadem Bar after The Queen?s speech and, later, a Yuletide buffet supper.

Guests staying three nights can dress in their best party outfit on Boxing Day evening for a champagne reception and black tie, four-course dinner before dancing the night away to the sounds of the 1960s, 70s and 80s.

Two and three night Christmas house party packages start from ?350 per person including festive menus and entertainment, children?s activities and use of the contemporary Vital Spa. Children aged 4 ? 12 years sharing with their parents pay just ?60 each per night dinner B&B and under 4s stay free.? To book call the Macdonald Berystede Hotel & Spa on 0844 879 9104 or visit www.MacdonaldHotels.co.uk/Berystede. hotel & Spa on 0870 400 8224,

Source: http://www.rustourismnews.com/?p=20715

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Church of England decision day on female bishops

LONDON (AP) ? The Church of England's governing body is voting on whether it will permit women to serve as bishops or continue debating the issue for several more years.

The push to muster a two-thirds majority among lay members of the General Synod is expected to be close on two votes, beginning with whether to adopt the legislation as English law. A second vote would follow on whether to incorporate the change in church law.

Votes among bishops and clergy in the synod are expected to pass easily. Archbishop Rowan Williams and his successor, Bishop Justin Welby, both strongly support the change.

If the measure fails, church officials say it could take five years to go through all the steps leading up to another vote.

Source: http://news.yahoo.com/church-england-decision-day-female-bishops-095917460.html

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San Diego panda cub is a 'little gift' (+video)

One hundred days after his birth, the San Diego Zoo's youngest panda received his name. Researchers say that due to the panda breeding program, the species survival seems more likely. ?

By Staff,?Associated Press / November 13, 2012

There is a new little gift at the San Diego Zoo that's going to get very big.

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The zoo's youngest giant?panda?was officially named Xiao Liwu, Chinese for "little gift," at a ceremony Tuesday. He is on the small side, but is strong and cooperative, said Dr. Ron Swaisgood, a member of the zoo's?panda?team.

The cub was born on July 29 and was named 100 days after its birth, according to Chinese zoo tradition. Officials said the cub weighs 9.2 pounds (4 kilograms) and stretches more than 23 inches (58 centimeters) long from nose to tail.

Zoo officials got 7,000 suggested names, chose their top six and put them up for a vote. More than 35,000 zoo visitors voted on names that meant Little Gift, Miracle, Raindrop, Big Ocean or Big Sea, Brave Son and Water Dragon.

Xiao Liwu's mother is Bai Yun which means White Cloud and father Gao Gao, which means Tall Tall. The cub is Bai Yun's sixth. She turned 21 in July, making her the oldest giant?panda?known to give birth.

Through participation in a?panda?exchange breeding program with China, researchers "have gone from zero to 100 overnight in understanding the species," Swaisgood said. That's very beneficial for conservation because "it's hard to conserve what we do not understand."

He called the?panda?the world's "best loved species."

Before the program, the future of the species was bleak, he said, because the death rate exceeded the birth rate. But in 2010, "we met the 200 individuals needed to preserve the genetic diversity of the species," Swaisgood said to applause from the audience.

Swaisgood described efforts by scientists in China to track wild?pandas. A wild?panda?will leave about 50 droppings a day, he said, and scientists can learn a lot from that, including information about DNA, hormones and diet.

Swaisgood said those taking part in the breeding program have done a good job.

"There is a feeling of hope that things are turning around for the species and it has a brighter future than it did 20 years ago," he said.

Source: http://rss.csmonitor.com/~r/feeds/science/~3/VjSmVhWKmV4/San-Diego-panda-cub-is-a-little-gift-video

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Home Based Business University - Internet Radio

Find out how to get the best haircut, color or style with tips from hair pro Ashley Mecham. We?ll also be taking questions for any of your hair-care needs so call in for your chance to win free Paula's Choice products!

Jolene Puffer welcomes Stacey Thureen as our guest for eFitFamily. She will share her thyroid journey and provide possible preventions to our beloved listeners.

Chat with actor, writer and director John Cabrera, who co-created the hot new web series produced by Bryan Singer (X-Men, Superman Returns) called H+: The Digital Series.

Kevin Howlett, editor of Colombia Politics, an English speaking online website about Colombia politics. We will discuss the current state of US-Colombia relations.

Please join me as I chat with actor, Eric Roberts, whose career has spun film, television and daytime. We will chat about his career, talk to fans and catch up with what he is working on now, plus connect with him with his fans.

Paul Gant's GO4IT(@goforitgant) will be be joined by one of the newest members of BET's hit series "The Game" actor Jay Ellis. Jay will discuss the show and some of the happenings in the NBA.

VividLife Radio?s Ed and Deb Shapiro welcome Jeff Brown author and Soul Shaper, to discuss his new book Ascending with both feet on the Ground a collection of author Jeff Brown?s most inspiring and well-loved Facebook quotes, soul-bytes, excerpts and aphorisms

WWE Survivor Series 2012 is tonight and on Tuesday, we will not only review Survivor Series, but also Monday Night Raw the following night!! Survivor Series is one of the top 4 shows of the entire wrestling year and this is a must feature event on BTR!!

Exclusive preview of Bio's HAUNTED ENCOUNTERS with stars Daniel, Jordan, Helmey - investigating the paranormal residue of America's darkest deeds

For his first feature film The Adventures of Priscilla Queen of the Desert Tim won an Oscar, British Academy of Film and Television Arts (BAFTA) award and Australian Film Institute (AFI) award for his costume design

David Venable is program host of the "In the Kitchen with David" show on the very popular cable tv retail shopping network, QVC. He drops by to discuss his brand new cookbook & his love of food.

Singer/songwriter Margo Rey revisits Olivia Wilder to talk about her booming career and her new CD, "Habit." Margo is offering 2 CDs and 2 Christmas 3-song EPs to 4 lucky live listeners!

The Drew Show welcomes Former MLB Pitcher Kerry Wood. Best known for his 20 strikeouts in one game against the Houston Astros. Now he has created with his wife 'The Wood Family Foundation' which helps intercity youth. Come hear this amazing story!

Best Ever You welcomes former NFL football player Vernon Turner. He played running back for six seasons and is the author of "The Next Level: A Game I Had To Play!"

Will Smith Sr, (proud father of actor, Will Smith), and Tony Smith will chat about their wonderful novel that's entitled "The Waymor". "It is a jazz club where you just might get way more than you bargained for!"

Nicholas Snow of Snow Biz Now welcomes Del Shores as he drops by the studios to discuss how his hit play, Southern Baptist Sissies, is being filmed for the big screen.

Rising star Rick Yune visits Movie Addict HQ to discuss playing a chilling James Bond villain in "Die Another Day" and a dashing hero in "Man with the Iron Fists." Yune, named one of People magazine's Sexiest Men, is the first Asian-American in Versace ads.

Real Sisters will be talking with wine expert, Sean Sullivan, of the Washington Wine Report, and getting his take on some of the best wines for the holidays. We welcome listener's calls and questions to help you navigate what can be a confusing choice.

Join SportsRantz.com's Anthony DiMoro & Katy Mitchel as they welcome MMA fighter Cassie Crisano to "The Rantin & Ravin Show" on SportsRantz Radio. Tuesday night 7pm EST

Wing Chun in the USA has become popular with such celebrities as Phil Morris & Robert Downey Jr. making it part of their lives, Wing Chun Grandmaster Jason Lau is the Pioneer in bringing Wing Chun to America, he will telling us his story.

This is the time of year people are thinking "next year I'm getting in shape" Our guest Robert Hopper is a renowned expert in the field of exercise with an emphasis on fun! Author of several books his latest, "Stick with Exercise For a Lifetime".

Special Agent Gregory K. Baker is a twenty-five year veteran of the FBI and has spent the majority of his career investigating and supervising agents and conducting criminal investigations in the FBI's Organized Crime/Violent Crime programs.

Kick Ass Fantasy Football is back for the 2012 Fantasy Football Season! We are here to help you Cruise to a Championship every Tuesday evening at 9:00 pm and Sunday at 11:00 am. 2 Great shows plus our anchor show Sunday Morning on 973ESPN.com and 97.3 ESPN

LOTL Welcomes Singer-Songwriter Tyme Johnson debut her latest CD "A Matter of Tyme: The Soundtrack This album is the Soundtrack to "A Matter of Tyme: The Book" It is the musical narration of the book. The songs were inspired by chapters in the book.

Tune in to listen to Season 1, Episode 4 of Verses and Flow Grammy-nominated Tyrese, and spoken word by Gina Loring and Pharoahe Monch Brought to you by lexus

Source: http://www.blogtalkradio.com/homebasedbusinessuniversity/2012/11/20/home-based-business-university

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How And Also Hardwearing . Brain And Muscle tissue Motivated Up ...

Everybody wants to get their body fit and healthy. Especially when summer season arrives and they want to look really good in their new bathing suits. But few people know how to begin in terms of feeling and looking match. The subsequent write-up gives you assistance on how to obtain that entire body you?ve usually wanted.

When you?ve been walking, exercising, jogging, or bicycling for a time, you must add hillsides into the route. Mountains are a fun way to make your system continue to work harder?you need a lot more strength to climb up them, plus more co-ordination and handle to keep on your own from tumbling lower them. Find a hilly course or use the incline over a treadmill machine to accomplish this.

Trip your cycling with one lower-leg! Utilizing just one single lower body at one time to launch your bike for short ranges will allow you to build-up even more of your leg muscle groups. By utilizing a single lower leg the two to force down on the pedal as well as pullup you will certainly be working several group of muscles. Your biking will increase considerably also.

To help keep yourself in great shape you should consist of strength training in your workouts. Strength training is fantastic mainly because it enables you to get rid of fat speedy and keep an excellent level of fitness. Without the need of incorporating strength training in your workout routines, you would have to job twice as tough or for a longer time in other locations to lose the excess fat.

If you are coping with a muscle tissue trauma, you must try to begin training it without delay. You should begin out at suprisingly low high intensity for only a few minutes or so. Whenever you really feel discomfort, instantly cease the exercise. Ice the region for approximately 20 mins following the workout. At some point, you need to experience the region come to be more powerful and much stronger, as time continues.

The true secret to greatest health and fitness is eating healthy. Eating healthy is simpler than most help it become to be. Consuming a variety of whole foods for each and every dish is all it takes. Ingesting a variety of meat, vegetables, fresh fruits, almonds and whole grains guarantees that you will be acquiring each of the nutrients and vitamins you will need.

An incredible fitness hint is to start off carrying out the counter hit. Bench demanding is the best exercising you can do in order to build up your pectoral muscles. You?ll wish to grab the pub at about arm thickness, then provide the club right down to your chest area. You?ll want to be sure you inhale also.

To develop durability, swiftly elevate light dumbbells. Working easily enables your muscle mass for very much vitality while they would if you were weightlifting more heavy dumbbells at a slow rate. For instance, on counter push, elevate forty to 60 pct of your respective optimum body weight and do seven sets of about three repetitions, accomplishing this as quickly as you are able to.

Given that you?ve concluded our post, you?re moving toward looking and feeling fantastic! Private fitness might not be a straightforward goal, but it?s one particular really worth striving for. Regardless of whether thing get tough, don?t surrender! If you find on your own seeking far more assist, there are numerous other assets around with some other pieces of assistance so that you can offer you that enhance.

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Source: http://articles.webdesignattitude.com/215776/fitness-2/muscle-building/how-and-also-hardwearing-brain-and-muscle-tissue-motivated-up.html

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